• Ahmad Aa Omer, Salman A Bin Dayel, Ali Sa Hummedi, and Noura Ia Almuhaimed.
• From the Department of Surgery (Omer) and Department of Medicine (Bin Dayel), Faculty of Medicine, Prince Sattam Bin Abdulaziz University, Al Kharj; from the Department of Medical Oncology (Hummedi), King Fahad Medical City; and from the MRI Department (Almuhaimed), King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.
• Saudi Med J. 2024 Mar 1; 45 (3): 288294288-294.

ObjectivesTo investigate the epidemiological and clinicopathological features of breast cancer (BC) in Saudi Arabia to improve decisions regarding resource allocation, disease control, and management.MethodsWe retrieved the records of all patients who presented with histologically proven BC at King Fahad Medical City between 2019 and 2020. The data were analyzed quantitatively, and the results were expressed as percentages and frequencies.ResultsThis study comprised 419 patients. The mean age was 50.13 (± 10.96) years. The majority of the patients were obese (56.6%), and approximately a quarter had a history of oral contraceptive pill use, breast biopsy, or an affected family member. Most cases were from the central region (80.1%), followed by the southern provinces (12.7%). Breast lumps were the most common complaint (89%), whereas hypertension and diabetes mellitus were the most common comorbidities. Invasive ductal carcinoma was the most common pathologic type (89.7%). Most patients presented with TNM stages II and III (55.2%), and 27.7% had metastasis. The main therapeutic modalities included radical mastectomy (63.8%), neoadjuvant chemotherapy (60.4%), and adjuvant radiotherapy (82.9%).ConclusionIn Saudi Arabia, a trend of BC incidence migration towards older patients may be ensuing. However, prediction of an advanced and aggressive presentation requires the enhancement of screening programs and standardized protocols for disease management.Copyright: © Saudi Medical Journal.

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