• Fuxing Li, Junqi Zhu, Yunwei Zheng, Youling Fang, Longhua Hu, and Jianqiu Xiong.
• From the Second Affiliated Hospital (Li, Zhu, Zheng, Fang, Hu), Jiangxi Medical College, Nanchang University; from the Department of Jiangxi Provincial Key Laboratory of Medicine (Li, Zheng, Hu), Clinical Laboratory of the Second Affiliated Hospital of Nanchang University; and from the Department of Nursing (Xiong), the Second Affiliated Hospital of Nanchang University, Jiangxi, China.
• Saudi Med J. 2024 Mar 1; 45 (3): 241251241-251.

ObjectivesTo compare the prognosis of bacteremic pneumonia caused by Klebsiella pneumoniae (K. pneumoniae) and Escherichia coli (E. coli) pathogens.MethodsA retrospective analysis was carried out on the clinical data of 162 patients who were diagnosed with bacterial pneumonia caused by either K. pneumoniae or E. coli between 2016-2019. The primary outcome of the analysis was the patients' 30-day mortality rate.ResultsThere were 82 patients in the E. coli bacteremic pneumonia (E. coli-BP) group and 80 patients in the K. pneumoniae bacteremic pneumonia (KP-BP) group. The 30-day mortality rate was 43.75% (n=35/80) in the KP-BP group and 21.95% (n=18/82) in the E. coli-BP group (p<0.001). Following the adjustment for confounding variables in 4 distinct models, the hazard ratios for the primary outcome in KP-BP were determined to be 0.70 (95% confidence interval [CI]: [0.44-1.02]) in Model 1, 0.72 (95% CI: [0.46-1.14]) in Model 2, 0.99 (95% CI: [0.57-1.73]) in Model 3, and 1.22 (95% CI: [0.69-2.18]) in Model 4.ConclusionPatients diagnosed with KP-BP exhibited a similar prognosis as those diagnosed with E. coli-BP. For patients with KP-BP, the risk of mortality was significantly higher for those who were in the intensive care unit, were infected with carbapenem-resistant strains, or had a high sequential organ failure assessment score. In patients with E. coli-BP, the Pitt bacteremia score was strongly associated with the 30-day mortality rate.Copyright: © Saudi Medical Journal.

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