• Medicine · Mar 2024

    Review

    Application of PLLA (Poly-L-Lactic acid) for rejuvenation and reproduction of facial cutaneous tissue in aesthetics: A review.

    • Yin-Jie Ao, Yan Yi, and Guo-Hui Wu.
    • Zhengxing Stomatological Hospital, Yichun City, Jiangxi Province, P.R. China.
    • Medicine (Baltimore). 2024 Mar 15; 103 (11): e37506e37506.

    AbstractPoly-L-lactin acid (PLLA) has been widely used in the field of bio-medicine. In 2004, as an injectable material, PLLA was approved by the FDA to treat AIDS-related facial atrophy. Since then, several injectable stuffs containing PLLA have been approved for marketing in various countries and regions. Recently, PLLA has often been used to treat facial rejuvenation problems like cutaneous depressions and static wrinkles which always induce unsatisfactory facial expression. This review introduces the physicochemical properties, regeneration stimulating mechanism, applications in aesthetics and injectable comorbidity of PLLA.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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