• World Neurosurg · Jun 2024

    Review Biography Historical Article

    Giuseppe Dagnini (1866-1928): Discoverer of the Trigemino-Cardiac Reflex and Practical Implications in Neurosurgery and other Medical Specialties.

    • Emanuele La Corte, GelmiClarissa Ann ElisabethCAENeurosurgery Unit, Department of Translational Medicine and for Romagna, University of Ferrara, Ferrara, Italy., Giacomo Bertolini, Federica Ruggiero, Iyan Younus, Carmelo Sturiale, Diego Mazzatenta, Alfredo Conti, and Raffaele Aspide.
    • Neurosurgery and Neurotraumatology Unit, Department of Neurosciences, IRCCS Ospedale Policlinico San Martino, Genova, Italy. Electronic address: emanuele.lacorte@hsanmartino.it.
    • World Neurosurg. 2024 Jun 1; 186: 116121116-121.

    AbstractThe authors present the life and art of Giuseppe Dagnini, a renowned Italian physician who was born in Bologna in 1866. He was the chief of the Maggiore Hospital in Bologna and authored valuable scientific works on the trigemino-cardiac reflex which is still applied in modern clinical practice. Dr. Dagnini firstly described the reflex in 1908 postulating that stimulation of one of the 3 branches of the trigeminal nerve triggers the afferent pathway in lowering heart rate. The authors also provide a modern outlook on the clinical implications of the TCR in neurosurgery, neuroanesthesia, and other medical specialties.Copyright © 2024 Elsevier Inc. All rights reserved.

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