• Pak J Med Sci · Nov 2013

    Case Reports

    Stevens Johnson Syndrome associated with Lamotrigine.

    • Shama Parveen and M Afzal Javed.
    • Dr. Shama Parveen, The Medical Centre, Manor Court Avenue, Nuneaton, CV11 5HX, UK.
    • Pak J Med Sci. 2013 Nov 1; 29 (6): 145014521450-2.

    AbstractStevens-Johnsons Syndrome (SJS) is an immune-complex-mediated hypersensitivity reaction and has been linked as an adverse side effects to many drugs. Lamotrigine, an anticonvulsive medication and also a commonly used mood stabiliser, can be associated with this adverse reaction. Although this has not been reported very commonly , SJS has high mortality and morbidity and requires careful attention as the use of Lamotrigine is increasing in clinical practice. We present a case where the patient developed Stevens - Johnson Syndrome three weeks after being started on Lamotrigine. The case is discussed for its relevance to the use of Lamotrigine which is currently prescribed very commonly in psychiatric practices.

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