• Chukwuka Elendu and Osinachi K Okoye.
• Department of Internal medicine, University of California, Santa Cruz, CA.
• Medicine (Baltimore). 2024 Mar 29; 103 (13): e37600e37600.

RationalePeripartum cardiomyopathy (PPCM) occurring in the context of hypertension presents a unique clinical challenge. This case contributes to the medical literature by highlighting the complexities of managing heart failure in postpartum women with pre-existing hypertensive disorders, particularly when complicated by a history of preeclampsia.Patient ConcernsMrs. O.O., a 34-year-old hypertensive woman, presented with progressive dyspnea, bilateral leg swelling, and orthopnea. Notably, she had a history of previous preeclampsia and exhibited worsening symptoms over several months.DiagnosesThe patient was diagnosed with decompensated heart failure secondary to PPCM, exacerbated by hypertension and anemia.InterventionsTherapeutic interventions included diuretics, angiotensin receptor-neprilysin inhibitors, digoxin, and anticoagulation. Additionally, lifestyle modifications and dietary restrictions were implemented.OutcomesFollowing treatment adjustments, the patient demonstrated significant improvement in symptoms, exercise tolerance, and cardiac function. The transition from NYHA class III to class II heart failure indicated successful management.LessonsThis case underscores the importance of a comprehensive approach to managing PPCM in hypertensive patients, with attention to cardiovascular and obstetric factors. It highlights the effectiveness of multidisciplinary care in achieving positive outcomes and emphasizes the need for heightened vigilance in postpartum women with cardiovascular risk factors.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.

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