• Arch Med Sci · Mar 2010

    Effects of drugs on the efficacy of radioiodine (|) therapy in hyperthyroid patients.

    • Lidia Oszukowska, Małgorzata Knapska-Kucharska, and Andrzej Lewiński.
    • Department of Nuclear Medicine and Oncological Endocrinology, Medical University of Lodz, Poland.
    • Arch Med Sci. 2010 Mar 1; 6 (1): 4104-10.

    AbstractThe treatment of hyperthyroidism is targeted at reducing the production of thyroid hormones by inhibiting their synthesis or suppressing their release, as well as by controlling their influence on peripheral tissue (conservative therapy, medical treatment). Radical treatment includes surgical intervention to reduce the volume of thyroid tissue or damage of the mechanisms of thyroid hormone synthesis by radioiodine ((131)|) administration. Radioiodine ((131)|) is a reactor radionuclide, produced as a result of uranium decomposition and emission of β and γ radiation. The therapeutic effects of the isotope are obtained by the emission of β radiation. In the paper, the effects of administered drugs (antithyroid, glucocorticosteroids, lithium carbonate, inorganic iodine, β-blockers) on the final outcome of radioiodine therapy in patients with hyperthyroidism are discussed.

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