• World Neurosurg · Jul 2024

    Review Case Reports

    Tumor or demyelination? Three tumefactive multiple sclerosis case reports and literature review.

    • Feiteng Qi, Yong Zhang, Xiang Li, Jie Fan, Haibo Tan, and Chao Quan.
    • Department of Neurology, Ningbo Medical Center Lihuili Hospital, Ningbo, China. Electronic address: qifeiteng@163.com.
    • World Neurosurg. 2024 Jul 1; 187: 141146141-146.

    ObjectiveTo investigate the clinical diagnosis and treatment of tumefactive multiple sclerosis (TMS).MethodsClinical data, laboratory and imaging examinations, and treatment of 3 patients with TMS were retrospectively analyzed. Data were further analyzed in relation to the literature.ResultsAll 3 patients had acute or subacute onset with large lesions on imaging, which were difficult to differentiate from tumors. Two cases had relapses on follow-up and one case had a stereotactic biopsy.ConclusionsTMS is difficult to differentiate from brain tumors. It is necessary to improve the understanding of these diseases, to apply the correct diagnosis and treatment and to avoid unnecessary invasive surgery and inappropriate treatment.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

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