• Daijiro Kabata, Noriko Saeki, Katsufumi Kajimoto, Riho Tanaka, Noriaki Kakiuchi, Ayumi Shintani, and Yukihiro Koretsune.
• Department of Medical Statistics, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan. Electronic address: daijiro.kabata@omu.ac.jp.
• Prev Med. 2024 Jun 1; 183: 107972107972.

IntroductionMetabolic syndrome increases the risk of cardiovascular events. Despite the Japanese healthcare system's efforts in early detection and intervention, particularly through Specific Health Checkup and Guidance programs, research on their effectiveness is limited. This study evaluated the impact of Specific Health Guidance on the predicted risk of atherosclerotic cardiovascular disease (ASCVD) in working-age Japanese individuals.MethodsEmploying an Interrupted Time Series (ITS) design, this study compared the trends in predicted ASCVD risk and each individual risk factor used for the prediction of ASCVD risk before and after intervention in individuals participating in the guidance.ResultsAnalyses based on the ITS design indicated that participation in Specific Health Guidance programs, specifically the intensive level program, mitigates the increase trend of the predicted ASCVD risk. On the other hand, the impact on the trends of individual cardiovascular risk factors was minimal.ConclusionsThe intensive level Specific Health Guidance appeared to reduce the increasing trend in ASCVD risk, emphasizing the importance of comprehensive risk assessment in evaluating health interventions. However, the results are limited owing to the specific demographics and short evaluation period. Further research is necessary to understand the long-term impacts and broader applicability.Copyright © 2024 Elsevier Inc. All rights reserved.

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