• Wiesław Tryniszewski, Mariusz Gadzicki, Zbigniew Maziarz, Jarosław Kuśmierczyk, Roman Goś, Jacek Rysz, and Maciej Banach.
• Department of Radiological, Isotopic Diagnostics and Therapy, Medical University of Lodz, Poland.
• Arch Med Sci. 2010 Dec 1; 6 (6): 904911904-11.

IntroductionThe objective of this study was to investigate the relationship between microvascular and macrovascular disturbances in patients with type 2 diabetes, as shown by results of ophthalmological examination and by vascular and perfusion examinations of the lower limbs.Material And MethodsA total of 85 patients with type 2 diabetes and an additional cardiovascular risk factor were enrolled in the study. All patients underwent complex ophthalmological examination, including fundus colour photography and fluorescein angiography, and were divided into two groups: group I with signs of diabetic non-proliferative retinopathy (NPDR), and group II with signs of diabetic proliferative retinopathy (P/PDR). After collection of the general medical history and analysis of medical data, patients underwent vascular and muscle perfusion examination of the lower limbs.ResultsIn the P/PDR group, disturbances of lower-limb perfusion were more frequent than in the NPDR group. Analysis of the blood flow and results of lower-limb muscle perfusion for the two groups showed a significant relationship with the severity of microvascular complications observed in examination of the fundus.ConclusionsOphthalmological assessment of the progression of diabetic retinopathy in patients with type 2 diabetes is a reliable indicator of the changes in peripheral vessel systems and perfusion defects in the lower limbs.

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