• Gordana Pavliša, Kristina Gašparović, Hrvoje Puretić, Lidija Ljubičić, Andrija Nekić, Vlasta Vuković, Katarina Vukančić, and Andrea Vukić Dugac.
• Jordanovac Department of Respiratory Diseases, Zagreb University Hospital Center, Zagreb, Croatia.
• Acta Clin Croat. 2023 Apr 1; 62 (Suppl1): 125131125-131.

AbstractCoronavirus disease 2019 (COVID-19) is presented with a wide range of symptoms, from asymptomatic disease to severe and progressive interstitial pneumonia. As part of interstitial pneumonia, respiratory failure is typically presented as hypoxia and is the most common cause of hospitalization. When oxygen therapy fails, continuous positive airway pressure (CPAP) or noninvasive mechanical ventilation (NIV) are used as respiratory support measures of first choice. Noninvasive respiratory support (NIRS) is applied in order to save intensive care unit resources and to avoid complications related to invasive mechanical ventilation. Emerging evidence has shown that the use of CPAP or NIV in the management of acute hypoxemic respiratory failure in COVID-19 reduces the need for intubation and mortality. The advantage of NIRS is the feasibility of its application on wards. NIV could be administered via a face mask or helmet interface. Helmet adheres better than mask and therefore leakage is reduced, a delivery of positive end-expiratory pressure is more accurate, and the risk of nosocomial transmission of infections is lowered. Patients on NIRS must be carefully monitored so that further respiratory deterioration is not overlooked and additional measures of care including timely intubation and invasive mechanical ventilation could be performed if needed.Sestre Milosrdnice University Hospital.

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