• Calvin J de Wijs, Stephan A C Schoonvelde, Egbert G Mik, Peter L de Jong, Michelle Michels, and Floor A Harms.
• Laboratory of Experimental Anesthesiology, Department of Anesthesiology, Erasmus Medical Center, University Medical Center Rotterdam, Rotterdam, the Netherlands. Electronic address: c.dewijs@erasmusmc.nl.
• J. Cardiothorac. Vasc. Anesth. 2024 Oct 1; 38 (10): 225422602254-2260.

ObjectivesHypertrophic obstructive cardiomyopathy (HOCM) may be treated by septal myectomy. Cardiac surgery-associated acute kidney injury (CSA-AKI) is a common complication, but little is known about its incidence after septal myectomy. The objectives of this work were to evaluate the prevalence of CSA-AKI after septal myectomy and identify potential perioperative and phenotype-related factors contributing to CSA-AKI.DesignThis was a retrospective database analysis with new data analysis.SettingThe study occurred in a single university academic expertise center for septal myectomy HOCM patients.ParticipantsData from 238 HOCM patients with septal myectomy operated on between 2005 and 2022 were collected.InterventionsCSA-AKI was stratified according to the Kidney Disease: Improving Global Outcomes (KDIGO) guidelines using measurement of creatinine and urine production. Important HOCM phenotype-related and perioperative factors were analyzed for their possible associations with CSA-AKI.Measurements And Main ResultsCSA-AKI occurred in 45% of patients; of these, 55% were classified as KDIGO stage I and the remaining 45% as stage II, with no chronic kidney damage observed. Moreover, there were no phenotypical or perioperative characteristics that were more prevalent in the CSA-AKI cohort. However, the use of beta-blockers and coronary artery disease were more prevalent in the CSA-AKI cohort.ConclusionsCSA-AKI is a common complication after septal myectomy but was transient, and kidney function recovered in all patients.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

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