• Arzneimittel Forsch · Jun 1999

    Clinical Trial

    Long-term intraspinal infusions of opioids with a new implantable medication pump.

    • R Likar, M C Spendel, W Amberger, B Kepplinger, S Supanz, and A Sadjak.
    • Department of Anaesthesiology and Intensive Care, General Hospital Klagenfurt, Austria.
    • Arzneimittel Forsch. 1999 Jun 1;49(6):489-93.

    AbstractExperiences with long-term intraspinal infusion of opioid drugs using the new implantable medication pump VIP 30 in patients with chronic non-malignant pain are reported. During a 19-month period 10 patients with chronic pain--mainly mixed nociceptive-neuropathic pain--underwent implantation of the medication pump for long-term treatment. The mean follow-up period was 9.5 months. Pain relief was classified as very good in 22.2%, good in 44.4%, moderate in 22.2% and poor in 11.1%. In 88.9% of the cases the patients stated they would undergo the same procedure again. Technical problems (catheter dislocation) developed in 1/10 patients could be surgically corrected. One pump including catheter was explanted because of an infected seroma within the pocket area. Long-term intrathecal application of opioids with the VIP 30 pumps is an effective and safe treatment in patients with chronic non-malignant pain.

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