• Ryouhei Akanabe, Ryoukichi Ikeda, Shigeru Kuwashima, Toshihiko Abe, Shinsuke Kaneshiro, Aya Katsura, Iori Kusaka, Yuki Kishima, and Kiyoto Shiga.
• Department of Otorhinolaryngology and Head-Neck Surgery, Iwate Medical University School of Medicine.
• Tohoku J. Exp. Med. 2024 Dec 11; 264 (2): 899289-92.

AbstractThe case report highlights the potential intracranial complications associated with otitis media, particularly cholesteatoma and mastoiditis, including meningitis, brain abscesses, epi- and subdural empyema, and sigmoid sinus thrombophlebitis. Pyogenic ventriculitis (PV), an inflammation of the ependymal lining of cerebral ventricles, is a rare but serious complication often secondary to factors such as meningitis, cerebral abscesses, or neurosurgery. The case presented involves a 52-year-old male with a history of head trauma who developed PV secondary to cholesteatoma. Despite initial challenges in diagnosis, timely antibiotic therapy and surgical intervention resulted in successful treatment. The study emphasizes the importance of considering ear diseases as potential sources of intracranial infection, particularly in cases of delayed symptom presentation or history of head trauma.

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