• African health sciences · Dec 2023

    Multicenter Study Observational Study

    Rising prevalence of gestational diabetes mellitus and its associated risk factors in Makurdi, North-Central Region of Nigeria.

    • Bruno Basil, Izuchukwu N Mba, Terna A Gav, Blessing K Myke-Mbata, Terrumun Z Swende, and Simeon A Adebisi.
    • Department of Chemical Pathology, Benue State University, Makurdi, Nigeria.
    • Afr Health Sci. 2023 Dec 1; 23 (4): 348355348-355.

    BackgroundThe disease burden of gestational diabetes mellitus (GDM) in sub-Saharan African region have been on the rise. Proper assessment of current prevalence of GDM may inform policy changes and management approach for improved care delivery.ObjectiveTo determine the current prevalence of Gestational Diabetes Mellitus (GDM) and evaluate its major risk factors amongst pregnant women in Makurdi, North-Central Nigeria.MethodThis was a multi-center hospital-based prospective observational study. Maternal characteristics and clinical risk factors for GDM in a cohort of 281 pregnant women at 9 to 16 weeks gestational age was evaluated. The one-step 75g oral glucose tolerance test (OGTT) was carried out at 24 to 28 weeks of gestation.ResultOf the 356 women recruited, 281 (79.8%) completed the study. The GDM prevalence in the cohort was 16.7%. Increased early pregnancy BMI (adjusted OR = 1.154, 95% CI = 1.080 - 1.233, p<0.001) and presence of family history of diabetes mellitus (adjusted OR = 0.482, 95% CI = 0.233 - 0.997, P<0.05) were independent risk factors for GDM in the cohort.ConclusionIncreasing maternal age and early pregnancy BMI amongst other possible reasons, may account for the rising prevalence of GDM in the region.© 2023 Basil B et al.

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