• John K Chae, Kate Rosen, Kyle Zappi, Alexandra Giantini-Larsen, Jenny Yan, Jeffrey Sung, Evan Bander, Theodore H Schwartz, John K Park, and Gayle Salama.
• Department of Neurological Surgery, NewYork-Presbyterian Weill Cornell Medicine, New York, New York, USA.
• World Neurosurg. 2024 Jul 1; 187: 288293288-293.

AbstractCerebrospinal fluid (CSF) leaks may occur at the skull base or along the spinal column and can cause a variety of debilitating neurological symptoms for patients. Recognizing the potential presence of a CSF leak and then identifying its source are necessary for accurate diagnosis and definitive treatment. A standardized workflow can be followed for successful leak localization, which often requires several diagnostic studies, and for definitive leak treatment, which can range from minimally invasive, needle-based approaches to a variety of surgical corrections. This review paper provides an overview of epidemiology, pathophysiology, and diagnostic workup for CSF leaks and introduces available treatment options. An illustrative case of a skull base CSF leak demonstrating diagnosis and surgical correction is provided.Copyright © 2024 Elsevier Inc. All rights reserved.

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