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Revista médica de Chile · Aug 2023
Review Case Reports[Atrioventricular block in granulomatosis with polyangiitis (Wegener's granulomatosis). Case report and review of literature].
- Luís Changuan R, René Asenjo G, Eduardo Sanhueza G, Raimundo Morris C, and Mario Ortíz O.
- Departamento Cardiovascular, Hospital Clínico Universidad de Chile, Santiago, Chile.
- Rev Med Chil. 2023 Aug 1; 151 (8): 108810921088-1092.
AbstractGranulomatosis with Polyangiitis (GPA), or Wegener's Granulomatosis, is an immunologically mediated systemic vasculitis of small and medium vessels, which commonly compromises the upper airway, lungs, and kidneys and is rarely associated with cardiac manifestations. Compromise of the cardiac conduction system is rare, and isolated cases of different degrees of atrioventricular block (AVB) have been described. We report a case of a 49-year-old male patient previously diagnosed with GPA 3 years ago, who presented to the emergency department with dyspnea, clinical signs of low output, bradycardia of 30/min, advanced second-degree AVB and complete left bundle branch block (LBBB) on the ECG. A literature review is presented, and we discuss the causes, evolution, and management of this GPA complication.
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