• Mayo Clinic proceedings · Sep 2024

    Case Reports

    Total Laryngeal Transplant in the Setting of Active Laryngeal Malignancy.

    • David G Lott, Girish K Mour, Danielle N Grandjean, Stephanie R C Zacharias, Elizabeth H Stearns, Brent A Chang, Payam Entezami, Michael L Hinni, Brittany E Howard, and Melissa Zheng.
    • Larynx and Trachea Transplantation Program, Mayo Clinic Arizona, Phoenix; Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic Arizona, Phoenix; Center for Regenerative Biotherapeutics, Mayo Clinic Arizona, Phoenix; Head and Neck Regenerative Medicine Laboratory, Mayo Clinic Arizona, Phoenix. Electronic address: hnrm@mayo.edu.
    • Mayo Clin. Proc. 2024 Sep 1; 99 (9): 144514481445-1448.

    AbstractLaryngeal transplant (LT) is a promising option to restore quality of life in patients with severe laryngeal dysfunction or a laryngectomy. These patients may be tracheostomy tube dependent or gastrostomy tube dependent and may lose their ability to verbally communicate. The loss of these important functions frequently results in social isolation and a severe decrease in quality of life. Laryngeal transplant has the potential to restore all of these important laryngeal functions. Herein, we report the first known documented LT performed in the setting of laryngeal chondrosarcoma.Copyright © 2024 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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