• Shelley J Duncan, Kamyla Marques, Jade Fawkes, Laura J Smith, and David T Wilkinson.
• Department of Sport and Health, Solent University, Southampton SO14 OYN, UK; School of Psychology, University of Kent, Canterbury, UK. Electronic address: shelley.duncan@solent.ac.uk.
• Neuroscience. 2024 Sep 13; 555: 178183178-183.

AbstractWe recently showed that vestibular stimulation can produce a long-lasting alleviation of motor features in Parkinson's disease. Here we investigated whether components of the motor related cortical response that are commonly compromised in Parkinson's - the Bereitschaftspotential and mu-rhythm event-related desynchronization - are modulated by concurrent, low frequency galvanic vestibular stimulation (GVS) during repetitive limb movement amongst 17 individuals with idiopathic Parkinson's disease. Relative to sham, GVS was favourably associated with higher amplitudes during the late and movement phases of the Bereitschaftspotential and with a more pronounced decrease in spectral power within the mu-rhythm range during finger-tapping. These data increase understanding of how GVS interacts with the preparation and execution of voluntary movement and give added impetus to explore its therapeutic effects on Parkinsonian motor features.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

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