• Saudi Med J · Aug 2024

    Case Reports

    Thrombocytopenia following iron repletion with ferrous gluconate.

    • Aljoharah A Al Saud, Muneerah R AlRomaizan, and Muath A Alkhunizan.
    • From the College of Medicine (Al Saud, AlRomaizan), Alfaisal University, and from the Department of Family Medicine and Polyclinic (Alkhunizan), King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
    • Saudi Med J. 2024 Aug 1; 45 (8): 848850848-850.

    AbstractImmune thrombocytopenia (ITP) is an autoimmune disorder marked by low platelet counts that puts patients at risk for spontaneous bleeding. A rare trigger for ITP is iron repletion, which has only been reported in a few cases. In this article, we present a unique case of a 54-year-old male with a history of recurrent ITP who experienced rapid thrombocytopenia following iron repletion with ferrous gluconate. Discontinuation of ferrous medications resulted in platelet counts returning to the normal baseline. Following more than 30 years of the patient's clinical timeline, this case demonstrates the chronic nature of ITP and the complexity of its causes. Further studies are needed to determine the prevalence of iron repletion-induced thrombocytopenia and its underlying mechanisms.Copyright: © Saudi Medical Journal.

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