• Amin Daoulah, Mohammed Alshehri, Prashanth Panduranga, Hatem M Aloui, Nooraldaem Yousif, Abdulrahman Arabi, Wael Almahmeed, Mohammed A Qutub, Ahmed Elmahrouk, Amr A Arafat, Omar Kanbr, Adnan Fathey Hussien, Mubarak Abdulhadi Aldossari, Abdulmohsen H Al Mefarrej, Tarique Shahzad Chachar, Haitham Amin, Gladsy Selva Livingston, Abeer Said Mohamed Al Rawahi, Jassim Alswuaidi, Shahrukh Hashmani, Mohammed Al Jarallah, Mohamed Ajaz Ghani, Badr Alzahrani, Maryam Jameel Naser, Wael Qenawi, Taher Hassan, Abdullah Alenezi, Ahmad S Hersi, Waleed Alharbi, Sultan Al Obaikan, Salman Saad Almalki, Sulafa Almukhtar Mohammed Ballool, Husam A Noor, Manar Khalid AlSuwaidi, Harvey Antony, Marwa Abd Elghany Albasiouny Alkholy, Khaled Alkhodari, Hassan Khan, Ali Alshehri, Ahmed A Ghonim, Seraj Abualnaja, Mokhtar Abdirahman Kahin, Rajesh Rajan, Khaled Almerri, Faisal Omar M Al Nasser, Ahmed Alhaydhal, Mohammed Awad Ashour, Omer A Elamin, Ahmed Jamjoom, Sary Mahmoud Wedinly, Youssef Elmahrouk, Ziad Dahdouh, Ethan M Ross, Said Al Maashani, Abdulwali Abohasan, Wael Tawfik, Mohammed Balghith, Abdelmaksoud Elganady, Ibrahim A M Abdulhabeeb, Rasha Mohammed Borini, Ayman Basardah, Abdulrahman M Alqahtani, Alaa Aldossari, Abdullah Omair Alsuayri, Mushira Khan, and Amir Lotfi.
• Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia.
• Shock. 2024 Aug 12.

BackgroundThere is a paucity of data regarding acute myocardial infarction (MI) complicated by cardiogenic shock (AMI-CS) in the Gulf region. This study addressed this knowledge gap by examining patients experiencing AMI-CS in the Gulf region and analyzing hospital and short-term follow-up mortality.MethodsThe Gulf-CS registry included 1,513 patients with AMI-CS diagnosed between January 2020 and December 2022.ResultsThe incidence of AMI-CS was 4.1% (1513/37379). The median age was 60 years. The most common presentation was ST-elevation MI (73.83%). In-hospital mortality was 45.5%. Majority of patients were in SCAI stage D and E (68.94%). Factors associated with hospital mortality were previous coronary artery bypass graft (OR:2.49; 95%CI: 1.321-4.693), cerebrovascular accident (OR:1.621, 95%CI: 1.032-2.547), chronic kidney disease (OR:1.572; 95%CI1.158-2.136), non-ST-elevation MI (OR:1.744; 95%CI: 1.058-2.873), cardiac arrest (OR:5.702; 95%CI: 3.640-8.933), SCAI stage D and E (OR:19.146; 95CI%: 9.902-37.017), prolonged QRS (OR:10.012; 95%CI: 1.006-1.019), right ventricular dysfunction (OR:1.679; 95%CI: 1.267-2.226) and ventricular septal rupture (OR:6.008; 95%CI: 2.256-15.998). Forty percent had invasive hemodynamic monitoring, 90.02% underwent revascularization, and 45.80% received mechanical circulatory support (41.31% had Intra-Aortic Balloon Pump and 14.21% had Extracorporeal Membrane Oxygenation/Impella devices). Survival at 12 months was 51.49% (95% CI: 46.44- 56.29%).ConclusionsThe study highlighted the significant burden of AMI-CS in this region, with high in-hospital mortality. The study identified several key risk factors associated with increased hospital mortality. Despite the utilization of invasive hemodynamic monitoring, revascularization, and mechanical circulatory support in a substantial proportion of patients, the 12-month survival rate remained relatively low.Copyright © 2024 by the Shock Society.

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