• Shock · Oct 2024

    Clinical outcomes of patients with cardiogenic shock complicating acute myocardial infarction: The Gulf-Cardiogenic Shock (G-CS) Registry.

    • Amin Daoulah, Mohammed Alshehri, Prashanth Panduranga, Hatem M Aloui, Nooraldaem Yousif, Abdulrahman Arabi, Wael Almahmeed, Mohammed A Qutub, Ahmed Elmahrouk, Amr A Arafat, Omar Kanbr, Fathey HussienAdnanADepartment of Cardiology, International Medical Center, Jeddah, Kingdom of Saudi Arabia., Abdulhadi AldossariMubarakMHeart Health Center, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia., Abdulmohsen H Al Mefarrej, Shahzad ChacharTariqueTDepartment of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Awali, Kingdom of Bahrain., Haitham Amin, Gladsy Selva Livingston, Mohamed Al RawahiAbeer SaidASDepartment of Cardiology, National Heart Center, Royal Hospital, Muscat, Sultanate of Oman., Jassim Alswuaidi, Shahrukh Hashmani, Mohammed Al Jarallah, Mohamed Ajaz Ghani, Badr Alzahrani, Jameel NaserMaryamMDepartment of Medicine, Baystate Medical Center, Springfield, Massachusetts., Wael Qenawi, Taher Hassan, Abdullah Alenezi, Ahmad S Hersi, Waleed Alharbi, Sultan Al Obaikan, Saad AlmalkiSalmanSHeart Health Center, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia., Mohammed BalloolSulafa AlmukhtarSAHeart Health Center, King Saud Medical City, Riyadh, Kingdom of Saudi Arabia., Husam A Noor, Khalid AlSuwaidiManarMDepartment of Cardiology, Mohammed Bin Khalifa Specialist Cardiac Center, Awali, Kingdom of Bahrain., Harvey Antony, Albasiouny AlkholyMarwa Abd ElghanyMAEDepartment of Cardiology, National Heart Center, Royal Hospital, Muscat, Sultanate of Oman., Khaled Alkhodari, Hassan Khan, Ali Alshehri, Ahmed A Ghonim, Seraj Abualnaja, Abdirahman KahinMokhtarMDepartment of Cardiology, International Medical Center, Jeddah, Kingdom of Saudi Arabia., Rajesh Rajan, Khaled Almerri, Faisal Omar M Al Nasser, Ahmed Alhaydhal, Mohammed Awad Ashour, Omer A Elamin, Ahmed Jamjoom, Sary Mahmoud Wedinly, Youssef Elmahrouk, Ziad Dahdouh, Ethan M Ross, Said Al Maashani, Abdulwali Abohasan, Wael Tawfik, Mohammed Balghith, Abdelmaksoud Elganady, Ibrahim A M Abdulhabeeb, Rasha Mohammed Borini, Ayman Basardah, Abdulrahman M Alqahtani, Alaa Aldossari, Abdullah Omair Alsuayri, Mushira Khan, and Amir Lotfi.
    • Department of Cardiovascular Medicine, King Faisal Specialist Hospital & Research Center, Jeddah, Kingdom of Saudi Arabia.
    • Shock. 2024 Oct 1; 62 (4): 512521512-521.

    AbstractBackground: There is a paucity of data regarding acute myocardial infarction (MI) complicated by cardiogenic shock (AMI-CS) in the Gulf region. This study addressed this knowledge gap by examining patients experiencing AMI-CS in the Gulf region and analyzing hospital and short-term follow-up mortality. Methods: The Gulf-Cardiogenic Shock registry included 1,513 patients with AMI-CS diagnosed between January 2020 and December 2022. Results: The incidence of AMI-CS was 4.1% (1,513/37,379). The median age was 60 years. The most common presentation was ST-elevation MI (73.83%). In-hospital mortality was 45.5%. Majority of patients were in SCAI (Society for Cardiovascular Angiography and Interventions shock classification) stage D and E (68.94%). Factors associated with hospital mortality were previous coronary artery bypass graft (odds ratio [OR]: 2.49; 95% confidence interval [CI]: 1.321-4.693), cerebrovascular accident (OR: 1.621; 95% CI: 1.032-2.547), chronic kidney disease (OR: 1.572; 95% CI: 1.158-2.136), non-ST-elevation MI (OR: 1.744; 95% CI: 1.058-2.873), cardiac arrest (OR: 5.702; 95% CI: 3.640-8.933), SCAI stage D and E (OR: 19.146; 95% CI: 9.902-37.017), prolonged QRS (OR: 10.012; 95% CI: 1.006-1.019), right ventricular dysfunction (OR: 1.679; 95% CI: 1.267-2.226), and ventricular septal rupture (OR: 6.008; 95% CI: 2.256-15.998). Forty percent had invasive hemodynamic monitoring, 90.02% underwent revascularization, and 45.80% received mechanical circulatory support (41.31% had intra-aortic balloon pump and 14.21% had extracorporeal membrane oxygenation/Impella devices). Survival at 12 months was 51.49% (95% CI: 46.44%-56.29%). Conclusions: The study highlighted the significant burden of AMI-CS in this region, with high in-hospital mortality. The study identified several key risk factors associated with increased hospital mortality. Despite the utilization of invasive hemodynamic monitoring, revascularization, and mechanical circulatory support in a substantial proportion of patients, the 12-month survival rate remained relatively low.Copyright © 2024 by the Shock Society.

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