• Jinhyun Kim.
• Division of Rheumatology, Department of Internal Medicine, Chungnam National University College of Medicine, Daejeon, Korea. md228@hanmail.net.
• Yonsei Med. J. 2024 Sep 1; 65 (9): 493500493-500.

AbstractCardiovascular involvement in Behçet's disease (BD) is considerably related to morbidity and mortality. However, the cardiovascular manifestation is sometimes difficult to distinguish from those of other causes. The suspicion of BD and proper treatment is pivotal in the management of BD. Histology demonstrates perivasculitis. Neutrophil seems to play an important role in the inflammation of BD. It is thought that inflammation causes venous thrombosis and arterial aneurysm. Characteristically, BD involves both arteries and veins of variable size in any region. Venous thrombosis needs immunosuppression, and inferior vena cava thrombosis and Budd-Chiari syndrome require intensive immunosuppressive therapy. Arterial involvement causes aneurysm which usually is treated by surgical or endovascular intervention with immunosuppression. Pulmonary artery aneurysm and cardiac involvement require multimodal managements.© Copyright: Yonsei University College of Medicine 2024.

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