• Medicina clinica · Dec 2024

    Meta Analysis

    Effectiveness of brain magnetic resonance imaging in the early diagnosis and characterization of dementias; a systematic review.

    • Ana María Ruiz Tornero, Esther E García Carpintero, and Begoña Rodríguez Ortiz de Salazar.
    • Servicio de Medicina Preventiva y Gestión de Calidad, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria, Madrid, España. Electronic address: artornero@salud.madrid.org.
    • Med Clin (Barc). 2024 Dec 13; 163 (11): 533548533-548.

    IntroductionMagnetic resonance imaging (MRI) is a frequently used test in the diagnosis of dementia. The objective was to evaluate its effectiveness for the early diagnosis of dementia in patients with mild cognitive impairment (MCI).Material And MethodsOriginal studies were selected from systematic reviews between 2011 and 2021, according to PRISMA 2020 criteria. QUADAS-2 and GRADE tools were used, and a meta-analysis was performed.ResultsFinal selection of 23 articles. Patient selection and index test had a high probability of bias. The certainty of the evidence was very low. In the hippocampus, sensitivity was 0.62 (95%CI 0.48-0.79) and specificity 0.70 (95%CI 0.55-0.80). In the temporal lobe, sensitivity was 0.65 (range 0.45) and specificity 0.69 (range 0.32).ConclusionsThere is insufficient evidence to recommend routine brain MRI for the early diagnosis of dementia in patients with MCI.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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