• Sait Kayhan, Şahin Kırmızıgöz, Alparslan Kırık, Özkan Tehli, and Yusuf İzci.
• Department of Neurosurgery, Gulhane School of Medicine, University of Health Sciences, Ankara, Turkey. Electronic address: dr.saitkayhan@icloud.com.
• World Neurosurg. 2024 Sep 4.

ObjectiveGraft failure is a common complication of cranioplasty.Revision cranioplasty is required to overcome this complication. However, no previous studies have reported outcomes in revision cranioplasty with three-dimensional (3D) custom-made titanium implants. We described our experience with 3D titanium implants in patients with revision cranioplasty.MethodsWe evaluated 43 consecutive patients who underwent revision cranioplasty using 3D custom-made titanium implants between January 2011 and December 2019.The 3D image of the patient's cranium and the plan to close the cranium defect were created in a virtual environment using software programs. Demographic and radiological features were compared based on the materials used in the initial cranioplasty.ResultsPrevious material was autologous graft (AG) in 27 patients and polymethyl methacrylate (PMMA) in 16 patients. The mean time without revision cranioplasty is longer in patients with PMMA implants than in patients with AG. There was no statistically significant difference in the length of hospital stay between patients with PMMA implants and patients with AG. There were no postoperative adverse events such as infection, wound dehiscence, convulsions, and epidural hematoma in 38 patients during hospitalization. Wound dehiscence developedin 5 patients and surgical repair was required in one.ConclusionInitial cranioplasty with PMMA provides a longer time period than the AG before the revision. However, both of them have similar outcomes based on length of hospital stay and cranial defect area. Custom-made 3D titanium implant is a good option for revision cranioplasty to prevent implant failure and reduce patients' cosmetic concerns.Copyright © 2024. Published by Elsevier Inc.

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