Primary adrenal insufficiency in adults: When to suspect, how to

Cleve Clin J Med · Sep 2024

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Primary adrenal insufficiency in adults: When to suspect, how to diagnose and manage.

Primary adrenal insufficiency is rare but serious; it puts patients at risk of acute decompensation and adrenal crisis due to insufficient cortisol and aldosterone production. Further, its diagnosis is often delayed, or it is mistaken for secondary adrenal insufficiency, which can have life-threatening consequences. Early recognition and appropriate treatment can greatly improve patient outcomes and quality of life.

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- Michelle D Lundholm, Jayachidambaram Ambalavanan, and Pratibha Pr Rao.
- Associate Staff, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, Cleveland, OH lundholmmichelle@gmail.com.
- Cleve Clin J Med. 2024 Sep 3; 91 (9): 553562553-562.
AbstractPrimary adrenal insufficiency is rare but serious; it puts patients at risk of acute decompensation and adrenal crisis due to insufficient cortisol and aldosterone production. Further, its diagnosis is often delayed, or it is mistaken for secondary adrenal insufficiency, which can have life-threatening consequences. Early recognition and appropriate treatment can greatly improve patient outcomes and quality of life.Copyright © 2024 The Cleveland Clinic Foundation. All Rights Reserved.

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Primary adrenal insufficiency in adults: When to suspect, how to diagnose and manage.

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