• Jamil M Obaid, Sultan A Saghir, Amir M Al-Hroob, Shaima A Mohammed, Ola'a A Melhi, Ashgan A Alhomamy, and Elham A Al-Qodaimi.
• From the Department of Medical Laboratory Sciences (Obaid, Mohammed), Faculty of Medicine and Health Sciences; from the Department of Medical Microbiology (Obaid), Faculty of Science, Ibb University, from the Department of Medical Laboratories (Obaid, Melhi, Alhomamy, Al-Qodaimi), Faculty of Medical Sciences, International Malaysian University, Ibb, Yemen, and from the Department of Medical Analysis (Saghir, Al-Hroob), Princess Aisha Bint Al-Hussein College of Nursing and Health Sciences, Al-Hussein Bin Talal University, Ma'an, Jordan.
• Saudi Med J. 2024 Oct 1; 45 (10): 106410701064-1070.

ObjectivesTo ascertain the prevalence of ABH antigen secretors and non-secretors among Yemenis. In addition to explore the factors that may affect the expression of the secretion phenotype.MethodsThis cross-sectional study was carried out between May and September 2022 on 215 healthy Yemeni individuals at the International Malaysian University, Ibb, Yemen. The participants were tested for blood group antigen on their blood samples using standard test tube method using the suitable ABH antisera. Saliva was collected and tested for secretion using hemagglutination inhibition test with suitable A, B, and H antisera. Before collecting the blood samples, informed consent was obtained from each participant and complete data and history questionnaire were collected by the research team.ResultsIn general, 78.1% of Yemini participants were found to be secretor (80% men and 73.3% females). This percentage increased within O blood group (95%) and decreased within AB blood group (54%) individuals. Both O and AB blood groups showed statistically significant association with secretor trait. Also, it was noticed that age advance increases the expression of Se gene. In addition, the secretor state increased among Rh-negative people.ConclusionThe frequency of ABH secretors was 78.1% among Ibb province population in Yemen. Blood group O revealed the greatest frequency (95%), whereas blood group AB showed the lowest secretor frequency (54%). The secretor phenotype was highly expressed gradually with advance age then decline.Copyright: © Saudi Medical Journal.

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