• Paula Anguita Gámez, Juan C Castillo Domínguez, José López Aguilera, Rafael González Manzanares, Álvarez-OssorioManuel PanMPUGC de Cardiología, Hospital Universitario Reina Sofía, IMIBIC, Universidad de Córdoba, Córdoba, España; CIBER Cardiovascular, España., and Manuel Anguita Sánchez.
• UGC de Cardiología, Hospital Universitario Reina Sofía, IMIBIC, Universidad de Córdoba, Córdoba, España; Facultad de Salud, HM Hospitales, Universidad Camilo José Cela, Madrid, España.
• Med Clin (Barc). 2024 Oct 15.

Introduction And ObjectivesInfective endocarditis (IE) caused by oral streptococci is considered to be a 'more benign' IE than those caused by other microorganisms. Our aim is to analyse the changes in its incidence and its differential characteristics in our setting.MethodsObservational, single-centre, prospective cohort study including all cases of IE diagnosed in our centre between 1987 and 2023. IE caused by oral streptococci were identified and their characteristicsand mortality were compared with those of other IE.ResultsOf 569 cases of IE, 104 (18.5%) were oral streptococcal IE, decreasing from 29.5% in 1987-1999 to 12.2% in 2000-2023 (p<0.001). The incidence of serious complications was lower in oral IE (65.3 vs. 78.9%; p=0.003), as was in-hospital mortality (14.4 vs. 29.9%; p=0.001).ConclusionsOral streptococcal IEs account for almost 20% of all IEs in our setting. They have a better prognostic clinical profile, with a lower incidence of serious complications, and their mortality is significantly lower than that of other IE. Their incidence seems to be decreasing in recent years.Copyright © 2024 Elsevier España, S.L.U. All rights reserved.

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