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- Dewu Bi, Xiaolu Luo, Xike Tang, Xiaocheng Luo, and Lida Mo.
- Department of Clinical Laboratory, The Fourth People's Hospital of Nanning, Nanning, China.
- Medicine (Baltimore). 2024 Oct 25; 103 (43): e40276e40276.
RationaleMeningitis caused by concurrent infections with Cryptococcus neoformans, Streptococcus equi subsp. equi, and Mycobacterium tuberculosis is extremely rare.Patient ConcernsWe present the case of a 63-year-old male patient who presented with headaches, dizziness, nausea, vomiting, and fever for the past 3 weeks.DiagnosesThe patient was diagnosed with concurrent cryptococcal, streptococcal, and tuberculous meningitis.InterventionsThe patient received isoniazid, rifampicin, ethambutol, and levofloxacin for 1 month, in addition to liposomal amphotericin B with flucytosine for 2 weeks, followed by fluconazole with flucytosine for additional 2 weeks.OutcomesThe symptoms improved, and outpatient therapy was continued.LessonsInfectious meningitis requires a combination of microscopy, culture, and rapid molecular diagnostics for early diagnosis and treatment.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.
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