• World Neurosurg · Nov 2024

    Application of computational fluid dynamic simulation of parent blood flow in the embolization of unruptured A1 aneurysms.

    • Gangqin Xu, Kun Zhang, Dongyang Cai, Bowen Yang, Tongyuan Zhao, Jiangyu Xue, Tianxiao Li, and Bulang Gao.
    • Division of Interventional Therapy Center, Cerebrovascular Disease Hospital, Henan Provincial People's Hospital, Cerebrovascular Division of Interventional Therapy Center, Zhengzhou University People's Hospital, Henan Provincial Neurointerventional Engineering Research Center, Zhengzhou, China.
    • World Neurosurg. 2024 Nov 12; 193: 696705696-705.

    ObjectiveTo investigate the effect of microcatheter shaping based on the parent artery mainstream line of blood flow simulated using the computational fluid dynamics (CFD) technique on embolization of unruptured aneurysms on the posterior wall of the anterior cerebral artery (ACA) A1 segment.MethodsPatients with unruptured cerebral aneurysms on the posterior wall of the ACA A1 segment were retrospectively enrolled and treated with endovascular embolization after microcatheter shaping. The clinical, embolization, and follow-up data were analyzed.ResultsEight patients were enrolled and treated with endovascular embolization. 8 microcatheters were steam-shaped in vitro and were all successfully navigated to the right location in the in vitro experiment. During the embolization procedure, 7 microcatheters were successfully navigated to the right location for embolization. In the remaining 1 patient who had tortuous cerebral arteries, reshaping of the microcatheter based on the parent artery mainstream of blood flow made successful navigation of the microcatheter to the right place. Complete occlusion was obtained in 7 (87.5%) aneurysms and residual aneurysm neck in the remaining 1 (12.5%). At angiographic follow-up in 6 (75%) patients, the Raymond grade was I in 5 (83.3%) and II in the rest 1 (16.7%).ConclusionsUse of computational fluid dynamics simulation of parent artery blood flow for microcatheter shaping in the embolization of unruptured aneurysms on the posterior wall of the ACA A1 segment is safe and effective in navigating the microcatheter to the right location for embolization, resulting in good stability and support for the embolization.Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…