• Hulya Y Ak, Kubra Taskin, Merve B Yediyildiz, Irem Durmus, Gulten Arslan, Sevda S Comert, Baris Sandal, and Kemal T Saracoglu.
• From the Department of Anesthesiology and Reanimation (Ak, Taskin, Yediyildiz, Durmus, Arslan); from the Department of Thoracic Medicine (Comert), Dr. Lutfi Kirdar City Hospital, from the Department of Biostatistics (Sandal), Faculty of Medicine, Istanbul University-Cerrahpaşa, Istanbul, Turkey, and from the Department of Anaesthesiology, ICU, and Perioperative Medicine (Saracoglu), Hazm Mebaireek General Hospital, Doha, Qatar.
• Saudi Med J. 2024 Nov 1; 45 (11): 122312271223-1227.

ObjectivesTo evaluate the clinical relevance of Integrated Pulmonary Index (IPI) monitoring during transbronchial needle aspiration (EBUS-TBNA) under sedation and determine whether it reduces hypoxic events compared to standard monitoring.MethodsThis prospective observational research was carried out at Dr. Lutfi Kirdar City Hospital, Istanbul, Turkey, between July 2022 and July 2023. A total of 50 patients, aged 18-80 years with American Society of Anesthesiologists scores of I-III, undergoing EBUS-TBNA with deep sedation for diagnostic purposes were included. The IPI values were measured at 6 time points: baseline, induction, 3, 5, 10 minutes, and at the end of the procedure. Patients were categorized based on whether their IPI scores were above 7 (group 1) or below 7 (group 2).ResultsA total of 43 patients completed the study. Group 1 had higher end-tidal carbon dioxide and respiratory rate at multiple time points, including induction and at 3, 5, and 10 minutes post-induction (p<0.05). Group 2 experienced a higher rate of apnea at these times (p<0.05). Those with lower IPI scores (namely, IPI=3 and IPI=4) showed significantly higher apnea rates, while those with higher scores (namely, IPI=7 and IPI=8) were less likely to have apneic episodes.ConclusionThe IPI monitoring during EBUS-TBNA under sedation demonstrated improved detection of apnea episodes and enhanced respiratory safety compared to standard monitoring techniques. Additional research involving more varied populations is necessary to confirm these results.Copyright: © Saudi Medical Journal.

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