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- Yue Guo, Yan Jiang, Hanbo Tang, Wenjuan Fan, Chenchen Ai, and Ping Liu.
- Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, China.
- Medicine (Baltimore). 2020 Feb 1; 99 (8): e19084e19084.
BackgroundSustained Inflations (SI) and Intermittent Positive Pressure Ventilation (IPPV) are two interventions to prevent Bronchopulmonary dysplasia (BPD). The aim of this study is to assess the effect of these two interventions.MethodsThe databases of PubMed, EMBASE, and Cochrane Central Register of Controlled Trials (CENTRAL) will be comprehensively searched from inception to September 2019. All RCTs and quasi-RCTs which compare the efficacy of SI vs IPPV among preterm infants are eligible. We will assess the methodological quality using the Cochrane Handbook version 5.1.0. A meta-analysis will be performed using RevMan 5.3 software and the results will be presented using risk ratios (RRs) and 95% confidence intervals (CIs).ConclusionsThis study will provide strong evidence for assessing the effect of SI and IPPV on BPD or death among preterm infants.Prospero Registration NumberCRD42019135816.
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