• Yangjie Yu and Qiying Chen.
• Yangjie Yu, Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, 200040, P.R. China.
• Pak J Med Sci. 2024 Dec 1; 40 (11): 258825932588-2593.

ObjectiveTo explore the impact of targeted lifestyle interventions on brain function in young and middle-aged patients with hypertension.MethodsClinical data of 104 young and middle-aged patients with hypertension, treated in Huashan Hospital, Fudan University from June 2021 to September 2023, were retrospectively analyzed. Forty nine patients received routine nursing care (control group), and 55 patients received targeted lifestyle interventions in addition to routine nursing care (observation group). Blood pressure levels, cognitive function, memory function, executive function, and working memory ability were compared between the two groups before and after the intervention.ResultsAfter the intervention, blood pressure levels in both groups decreased compared to before the intervention, and were significantly lower in the observation group compared to the control group (P<0.05). After the intervention, both groups showed significant improvements in cognitive function, memory function, executive function, and working memory ability (P<0.05).ConclusionsTargeted lifestyle interventions can significantly improve blood pressure control levels and brain function in young and middle-aged patients with hypertension.Copyright: © Pakistan Journal of Medical Sciences.

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