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J Pain Palliat Care Pharmacother · Dec 2024
Case Report: Buprenorphine for Palliation in a Patient with End Stage Renal Disease.
- Sing Ping Chow, Scott Donelenko, and Chris Coppock.
- Pharmacy Pain Service, Bay Pines Veterans Health System, Bay Pines, Florida, USA.
- J Pain Palliat Care Pharmacother. 2024 Dec 5: 141-4.
AbstractEnd stage renal disease (ESRD) is known to be associated with pain, malaise and decreased quality of life. Pain management in the setting of dialysis is particularly challenging from a pharmacologic standpoint given altered pharmacokinetics of pain medications. Buprenorphine, a partial mu opioid receptor agonist, demonstrates superior safety profile compared to full mu opioid receptor agonists. In this case report, we demonstrated buprenorphine buccal film (Belbuca) as a safe and effective opioid treatment option for pain palliation in a dialysis dependent patient. Future studies may be warranted with larger sample size and longer follow up period to study the effect of buprenorphine in the setting of hemodialysis and non-dialysis dependent ESRD population.
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