• Zhiqiang Wang and Wendy E Hoy.
• Department of Medicine, School of Medicine - Central Clinical Division, University of Queensland, F4, Block 6, Royal Brisbane Hospital, Herston. zwang@ccs.uq.edu.au
• Med. J. Aust. 2004 May 17; 180 (10): 508511508-11.

ObjectivesTo determine the incidence rate of coronary heart disease (CHD) in Australian Aboriginal people with type 2 diabetes, and to compare the impact of diabetes on CHD risk in Aboriginal women and men.DesignCohort study.SettingA remote Aboriginal community in the Northern Territory.Participants889 Aboriginal people aged 20-74 years followed up to 31 May 2003 after baseline examination in 1992-1995.Main Outcome MeasuresIncidence rates of CHD (estimated for 123 participants with diabetes at baseline and 701 "non-diabetes" participants); rate ratios for diabetes risk (95% CI), with "non-diabetes" participants as the reference group.ResultsParticipants with diabetes at baseline had a higher rate of CHD (37.5 per 1000 person-years) than those without diabetes (7.3 per 1000 person-years). Adjustment for multiple CHD risk factors, such as age, smoking, alcohol consumption, systolic blood pressure, body mass index, high-density lipoprotein cholesterol and total cholesterol levels, resulted in a CHD rate ratio for women of 3.7 (95% CI, 1.6-8.9) (comparing women with diabetes with those without) and a CHD rate ratio for men of 1.4 (95% CI, 0.4-4.1) (comparing men with diabetes with those without).ConclusionsAboriginal women with diabetes experienced a significantly higher risk of CHD than women without diabetes. Although the difference was not statistically significant, women with diabetes had a higher CHD risk than men with diabetes.

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