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Comparative Study
Seroconversion after administration of measles vaccine to central Australian Aboriginal children at nine months of age.
- J N Hanna, A B Macintyre, D A Worswick, and C J Burrell.
- Northern Territory Department of Health and Community Services, Alice Springs.
- Med. J. Aust. 1989 Feb 20; 150 (4): 188192188, 191-2.
AbstractA simple procedure for examining the seroconversion rates to measles vaccines in outlying communities is described; this involves the storage and transportation of dried-blood samples on filter paper, which is followed by the detection of measles-specific antibodies by means of a commercially-available immunofluorescence assay. Among 82 susceptible central Australian Aboriginal infants who were vaccinated at nine months of age, 76 (93% [95% confidence limits, 84.9%-96.6%]) children demonstrated seroconversion as a result of the vaccine, which is a figure that is similar to those that have been reported from some developing countries. The implications for a measles-vaccination policy are discussed.
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