• Eur. J. Clin. Invest. · Oct 1992

    Randomized Controlled Trial Clinical Trial

    The effects of dietary supplementation with n-3 polyunsaturated fatty acids in patients with rheumatoid arthritis: a randomized, double blind trial.

    • G L Nielsen, K L Faarvang, B S Thomsen, K L Teglbjaerg, L T Jensen, T M Hansen, H H Lervang, E B Schmidt, J Dyerberg, and E Ernst.
    • Department of Rheumatology, Aalborg Hospital, Copenhagen, Denmark.
    • Eur. J. Clin. Invest. 1992 Oct 1; 22 (10): 687691687-91.

    Study ObjectiveTo determine the effect of dietary supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) on disease variables in patients with rheumatoid arthritis.DesignMulticenter, randomized, placebo controlled, double blind.SettingThree Danish hospital Departments of Rheumatology.PatientsFifty-one patients with active rheumatoid arthritis.InterventionRandom allocation to 12 weeks of treatment with either six n-3 PUFA capsules (3.6 g) or six capsules with fat composition as the average Danish diet.Main ResultsSignificant improvement of morning stiffness and joint tenderness. No significant effect on the four other assessed clinical parameters. No serious side effects.ConclusionsDietary supplementation with n-3 PUFA in patients with rheumatoid arthritis improved two out of six patient reported disease parameters. Further studies are needed to clarify the more precise role of n-3 PUFA in the treatment of rheumatoid arthritis.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…