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Ann Fr Anesth Reanim · Jul 2003
Randomized Controlled Trial Comparative Study Clinical Trial[Topical methylprednisolone vs lidocaïne for the prevention of postoperative sore throat].
- B Lévy, F Mouillac, D Quilichini, J Schmitz, J Gaudart, and F Gouin.
- Département d'anesthésie-réanimation, CHU La Timone, 264, rue Saint-Pierre, 13005 Marseille, France. barbaralevy@doctor.com
- Ann Fr Anesth Reanim. 2003 Jul 1; 22 (7): 595-9.
ObjectiveWe assessed the efficacy of topical methylprednisolone or lidocaine for prevention of postoperative sore throat.Study DesignRandomised, prospective in single blind study.Patients And MethodsSixty patients ASA 1 or 2 undergoing tracheal intubation for dental surgery received before intubation either topical lidocaine 5% (15 puffs) or aerosolized methylprednisolone (80 mg). Postoperative pain was assessed by the patients using a VAS and a specific scoring system for sore throat, cough and hoarseness. Evaluations were performed immediately after emergence from anaesthesia, 1 h later, at time of the first postoperative drink, at time of the first postoperative meal and 24 h after surgery.ResultsPatients receiving methylprednisolone showed slightly better scores for sore throat and cough 1 h after surgery.ConclusionTopical methylprednisolone may therefore be a useful adjuvant in the prevention of sore throat after intubation.
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