• Cleve Clin J Med · Jan 2025

    Review

    Insomnia in older adults: A review of treatment options.

    • Roberto León-Barriera, Margaret M Chaplin, Jasleen Kaur, and Vania Modesto-Lowe.
    • Assistant Professor, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA leonbarrierara@upmc.edu.
    • Cleve Clin J Med. 2025 Jan 2; 92 (1): 435043-50.

    AbstractInsomnia is a common and challenging complaint in older adults (> 65 years) because of age-related alterations in sleep physiology. Cognitive behavioral therapy for insomnia is the gold standard for treatment of insomnia in young as well as older patients. Both clinicians and patients often prefer the simplicity of medication, but risks associated with some hypnotics increase with age. Pharmacologic options for older adults include low-dose doxepin, melatonin, ramelteon, and the dual orexin receptor antagonists. A well-informed clinician can help patients navigate the risks and benefits of both pharmacologic and behavioral options.Copyright © 2025 The Cleveland Clinic Foundation. All Rights Reserved.

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