• Gac Med Mex · Jan 2024

    Review

    Assessment of fracture risk with FRAX and FRAXplus.

    • Teck H A Tan, Helena Johansson, Nicholas C Harvey, Mattias Lorentzon, John A Kanis, Eugene McCloskey, and Marian Schini.
    • Fast and Chronic Programmes, Alexandra Hospital, Singapore.
    • Gac Med Mex. 2024 Jan 1; 160 (4): 363373363-373.

    AbstractFRAX®, a risk calculator that provides individualized 10-year probabilities of hip and major osteoporotic fracture, has been widely used for fracture risk assessment since its launch in 2008. It is now incorporated into very many guidelines worldwide to inform osteoporosis management. In this review, we explore the development of FRAX and how it enhances fracture risk prediction as compared to use of bone mineral density alone, as well as approaches to utilizing FRAX in determining intervention and assessment thresholds. We also discuss the limitations of FRAX and the arithmetic adjustments that have been proposed to address these. The introduction of FRAXplus® includes these adjustments on a web-based platform for ease of application to enhance treatment decisions in osteoporosis.Copyright: © 2024 Permanyer.

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