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Editorial Comment
The gut-brain axis in the critically ill: Is glucagon-like peptide-1 protective in neurocritical care?
- Mark P Plummer, Juris J Meier, and Adam M Deane.
- Crit Care. 2013 Jan 1;17(4):163.
AbstractEnteral nutrient is a potent glucagon-like peptide-1 (GLP-1) secretagogue. In vitro and animal studies indicate that GLP-1 has immune-modulatory and neuroprotective effects. To determine whether these immune-modulatory and neuroprotective effects of GLP-1 are beneficial in the critically ill, studies achieving pharmacological GLP-1 concentrations are warranted.
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