• N D Clement, D MacDonald, R Burnett, and S J Breusch.
• Department of Orthopaedics and Trauma, The Royal Infirmary of Edinburgh, Little France, Edinburgh, EH16 4SA, UK. Electronic address: nickclement@doctors.org.uk.
• Knee. 2013 Dec 1;20(6):437-41.

BackgroundThere is conflicting evidence as to whether diabetes mellitus influences the functional outcome and patient satisfaction after a total knee replacement (TKR). The aim of this study was to assess the effect of diabetes upon the Oxford knee score (OKS), short form (SF)-12, and patient satisfaction after TKR.MethodsProspective pre- and post-operative (one year) OKS and SF-12 scores for 2389 patients undergoing primary TKR were compiled, of which 275 (12%) patients suffered with diabetes. Patient satisfaction was assessed at one year.ResultsPatients with diabetes were more likely to have a greater level of comorbidity (p<0.001), and a worse pre-operative OKS and SF-12 score (p<0.02), compared to those patients without diabetes. Diabetes was not a significant (p>0.41) independent predictor of post-operative OKS or the SF-12 physical score on multivariable analysis. Although, factors more prevalent within the diabetic cohort (heart disease, vascular disease, liver disease, anaemia, depression, back pain, worse pre-operative OKS and SF-12 score) were found to be independent predictors of post-operative OKS and SF-12 physical score. Interestingly, diabetes was associated with a significantly greater improvement in mental wellbeing (SF-12 mental component), which was confirmed on multivariable analysis. Patient satisfaction was not influenced by a concomitant diagnosis of diabetes (p=0.57).ConclusionThe outcome of TKR as assessed by the OKS, SF-12, and overall patient satisfaction rates are not influenced by diabetes per se, although factors more prevalent within this population result in a worse post-operative outcome.Level Of Evidenceprospective cohort study, level III.Copyright © 2013 Elsevier B.V. All rights reserved.

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