• Ann Fr Anesth Reanim · Oct 1999

    Case Reports

    [Severe anaphylactic reactions after administration of rocuronium].

    • Y Barthelet, Y Ryckwaert, C Plasse, M C Bonnet-Boyer, and F d'Athis.
    • Département d'anesthésie-réanimation A, hôpital Lapeyronie, Montpellier, France.
    • Ann Fr Anesth Reanim. 1999 Oct 1;18(8):896-900.

    AbstractThe authors report four cases of severe anaphylactic reactions (grade III or IV) to rocuronium bromide. In three of them, it was the first contact with a muscle relaxant. In three patients the reaction was mediated by IgE anti-bodies. A cross-reactivity with other muscle relaxants was existing in two cases (suxamethonium, vecuronium and atracurium in one patient, suxamethonium, vecuronium and pancuronium in the other.

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