• Saudi J Kidney Dis Transpl · Nov 2014

    Case Reports

    Continuous venovenous hemodiafiltration along with charcoal hemoperfusion for the management of life-threatening lercanidipine and amlodipine overdose.

    • Prashant Nasa, Akhilesh Singh, Deven Juneja, Omender Singh, and Yash Javeri.
    • Department of Critical Care Medicine, Max Superspeciality Hospital, New Delhi, India.
    • Saudi J Kidney Dis Transpl. 2014 Nov 1;25(6):1255-8.

    AbstractOverdose with calcium channel blockers is uncommon, but is associated with high mortality. The management includes fluid resuscitation, calcium gluconate, glucagon, vasopressors, and high-dose insulin-euglycemia therapy. We describe a rare case of massive overdose of lercanidipine with shock, refractory to conventional therapies and multi-organ failure. Charcoal hemoperfusion with continuous venovenous hemodiafiltration was then used successfully and the patient showed remarkable recovery.

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