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Postgraduate medicine · Jul 2009
ReviewThe role of RAS modification for primary and secondary stroke prevention.
- Dan J Fintel.
- Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. dfintel@northwestern.edu
- Postgrad Med. 2009 Jul 1;121(4):115-22.
AbstractClinical trial results indicate that the choice of antihypertensive agent can be a determinant of stroke protection, independent of blood pressure (BP) reduction. Angiotensin-converting enzyme inhibitors (ACE-Is) are effective for BP control and stroke protection, but their use may be limited by patient tolerability. Angiotensin receptor blockers appear to provide similar BP control compared with ACE-Is and may also offer the clinician the added benefit of primary and secondary stroke prevention, with the potential for fewer tolerability issues.
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