• Postgraduate medicine · Jul 2009

    Review

    The role of RAS modification for primary and secondary stroke prevention.

    • Dan J Fintel.
    • Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. dfintel@northwestern.edu
    • Postgrad Med. 2009 Jul 1;121(4):115-22.

    AbstractClinical trial results indicate that the choice of antihypertensive agent can be a determinant of stroke protection, independent of blood pressure (BP) reduction. Angiotensin-converting enzyme inhibitors (ACE-Is) are effective for BP control and stroke protection, but their use may be limited by patient tolerability. Angiotensin receptor blockers appear to provide similar BP control compared with ACE-Is and may also offer the clinician the added benefit of primary and secondary stroke prevention, with the potential for fewer tolerability issues.

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