• Wolfgang Eberle, Julien Penders, and Refet Firat Yazicioglu.
• Imec, Leuven, Belgium. wolfgang.eberle@imec.be
• Conf Proc IEEE Eng Med Biol Soc. 2011 Jan 1;2011:1556-8.

AbstractDEEP brain stimulation implants have improved life quality for more than 70,000 patients world-wide with diseases like Parkinson's, essential tremor, or obsessive-compulsive disorder where pharmaceutical therapies alone could not offer sufficient relief. Still, optimization and monitoring relies heavily on regular clinical visits, putting a burden on patient's comfort and clinicians. Permanent monitoring and combination with other patient health signals could ultimately lead to a personalized closed-loop therapy with remote quality monitoring. This requires technological improvements on the DBS implants such as integration of recording capabilities for brain activity monitoring, active low-power electronics, rechargeable battery technology, and body sensor networks for integration with e.g. gait, speech, and other vital information sensors on the patient's body and a link to a telemedicine platform using mobile technologies.

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