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- Rachael L Parke, Michelle L Eccleston, and Shay P McGuinness.
- Cardiothoracic and Vascular ICU, Auckland City Hospital, Auckland, New Zealand. rparke@adhb.govt.nz
- Resp Care. 2011 Aug 1;56(8):1151-5.
BackgroundNasal high-flow oxygen therapy increases the mean nasopharyngeal airway pressure in adults, but the relationship between flow and pressure is not well defined.ObjectiveTo determine the relationship between flow and pressure with the Optiflow nasal high-flow oxygen therapy system.MethodsWe invited patients scheduled for elective cardiac surgery to participate. Measurements were performed with nasal high-flow oxygen at flows of 30, 40, and 50 L/min, with the patient's mouth both open and closed. Pressures were recorded over one minute of breathing, and average flows were calculated via simple averaging.ResultsWith the mouth closed, the mean ± SD airway pressures at 30, 40, and 50 L/min were 1.93 ± 1.25 cm H(2)O, 2.58 ± 1.54 cm H(2)O, and 3.31 ± 1.05 cm H(2)O, respectively. There was a positive linear relationship between flow and pressure.ConclusionsThe mean nasopharyngeal pressure during nasal high-flow oxygen increases as flow increases. Australian Clinical Trials Registry http://www.adhb.govt.nz/achicu/hot_2_airway_pressure.htm.
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