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- Deborah Lehman, Ching Wen Tseng, Samantha Eells, Loren G Miller, Xuemo Fan, David O Beenhouwer, and George Y Liu.
- Division of Pediatric Infectious Diseases, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.
- Clin. Infect. Dis. 2010 Jan 1;50(1):69-72.
AbstractThe incidence of myositis has been increasing since the advent of the epidemic of community-associated methicillin-resistant Staphylococcus aureus infection, and Panton-Valentine leukocidin has been implicated as a factor contributing to more-severe muscle injury. We report a case of severe myositis accompanying septic osteomyelitis and necrotizing fasciitis caused by a Panton-Valentine leukocidin-positive S. aureus strain. Immunostaining showed strong binding of the Panton-Valentine leukocidin toxin to necrotic muscle tissues.
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