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Bull. Exp. Biol. Med. · Aug 2014
Functional and metabolic changes in the brain in neuropathic pain syndrome against the background of chronic epidural electrostimulation of the spinal cord.
- A A Sufianov, A G Shapkin, G Z Sufianova, V G Elishev, D A Barashin, V B Berdichevskii, and S V Churkin.
- Federal Center of Neurosurgery, Ministry of Health of the Russian Federation, Tyumen, Russia, sufianov@mail.ru.
- Bull. Exp. Biol. Med. 2014 Aug 1;157(4):462-5.
AbstractChanges in functional and metabolic activities of the brain were evaluated by EEG and positron-emission/computer tomography with 18F-fluorodeoxyglucose in patients with neuropathic pain syndrome previous to and 3 months after implantation of a system for chronic epidural spinal cord stimulation. In most cases, the use of a nerve stimulator was followed by alleviation of neuropathic pain and partial normalization of functional and metabolic activities of brain structures responsible for pain perception, emotiogenic, behavioral, and autonomic responses.
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